• Comparative pathologists are available for consultation or collaboration
  • Phenotyping of genetically modified mice
  • Experience in preclinical toxicology studies
  • Project consultation during initial study design, execution, analysis, and publication preparation
  • Concise morphologic diagnoses using standardized consensus nomenclature
  • Standardized scoring systems for neoplastic, inflammatory, and other non-neoplastic lesions
  • Cause of death assignments, co-morbidity, and disease burden quantification
  • Customized methods development for project-specific pathology objectives
  • Publication quality photomicrographs and virtual slide annotation
  • Comparison and validation of rodent models to human conditions


  • Tissue processing, embedding, sectioning (both paraffin and frozen)
  • H&E and special stains


  • Simplify and improve the consistency of your immunohistochemistry
  • Numerous optimized protocols for mouse, rat and human antigens
  • We can develop new immunostaining protocols for your antibodies
  • Optimized antibodies


  • Hamamatsu Nanozoomer Digital Pathology system
  • Automatically scans and archives up to 210 slides at a time
  • Online access to your images via secure login
  • Click here to view NDP.view procedures (PDF)


  • Visiopharm software that automates image analysis and stereology using whole slide digital images
  • Nikon Elements and ImagePro Software


  • Fully automated Nikon 90i scope with DIC, multi-channel fluorescence, and Nikon DiR1 color and Cool-Snap monochromatic digital cameras
  • Applied Precision’s state-of-the-art Delta Vision Core Microscope with deconvolution software.  Excellent for tissue and live cell imaging studies.


  • On-site training in all technologies and equipment
  • Organized workshops on immunohistochemistry, microscopy, image analysis, stereology, pitfalls with fluorescence and digital imaging, and pathology of mouse models of human diseases


  • Luminex Bio-Plex 200.  Screening and performance assays for simultaneously detecting and quantifying multiple target analytes in qualified complex sample types